In 1272, ten years after Shinran’s death, his daughter Kakushin-ni and her husband moved Shinran’s gravesite to their own parcel of land and built a memorial hall where his ashes and image were enshrined. This memorial hall eventually became the original Honganji temple. When Rennyo (1415–1499) was the head priest of the temple, the Honganji was destroyed and he had to move around from one place to another where he continued to lay the foundations of the sangha through his propagation efforts. He eventually rebuilt the Honganji temple in Yamashina, Kyoto and later in Osaka as well, both of which would be destroyed in conflicts again.
During those times, Shinran’s ashes are believed to have been protected at the original site of the Honganji by a follower’s family for generations, though they also had to evacuate their place a few times due to the conflicts. After the Higashi Honganji was established at its present site in 1603, a temporary memorial hall was built in the temple precincts where the ashes of Shinran and his descendants were enshrined.
In the 1660s, the temple acquired a parcel of land at the present site of the Ōtani Mausoleum (Ōtani Sobyō), which is close to the original burial site of Shinran, and relocated the ashes of Shinran and others there in 1670. This is the beginning of today’s Ōtani Mausoleum. After its establishment, the mausoleum went through a number of renovations. In the 1800s, it acquired an additional parcel of land of about 8 acres, by which the precincts of the Ōtani Mausoleum were significantly expanded.